Chitosan
A fiber-like compound derived from shellfish that may help with weight loss and cholesterol reduction.
Overview
Chitosan is a sugar that is obtained from the hard outer skeleton of shellfish, including crab, lobster, and shrimp. It is used for medicine. Chitosan is used to treat obesity, high cholesterol, and Crohn's disease. It is also used to treat complications that kidney failure patients on dialysis often face, including high cholesterol, “tired blood” (anemia), loss of strength and appetite, and trouble sleeping (insomnia). Some people apply chitosan directly to their gums to treat inflammation that can lead to tooth loss (periodontitis), or chew gum that contains chitosan to prevent “cavities” (dental caries).
Key Benefits
May Aid in Weight Loss
Chitosan is believed to bind to fat in the digestive tract, preventing it from being absorbed by the body.
May Lower Cholesterol
Some studies suggest that chitosan can help lower cholesterol levels by binding to bile acids in the intestines.
Dosage & How to Take
For weight loss, a common dosage is 1-4.5 grams of chitosan daily, taken in divided doses before meals.
| Purpose | Dose | Notes |
|---|---|---|
| Weight Loss | 1-4.5 grams daily | Taken in divided doses before meals. |
| High Cholesterol | 1-4.5 grams daily | Taken in divided doses before meals. |
Best Time to Take
Take before meals to maximize its fat-binding effects.
With or Without Food
Take with a full glass of water before meals.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules | Medium | Convenient dosing for weight loss and cholesterol management | Widely available as a dietary supplement. |
Side Effects & Safety
Common
- Constipation
- Gas
- Upset stomach
Rare
- Allergic reactions in people with shellfish allergies
Contraindications
- Shellfish allergy
- Pregnancy and breastfeeding
Interactions
May increase the effects of warfarin, increasing the risk of bleeding.
May decrease the absorption of these vitamins.
Scientific Research
Chitosan for weight loss
A 2007 review of studies found that chitosan may have a small effect on body weight, but the quality of the studies was low.
The effect of chitosan on body weight: a systematic review and meta-analysis of randomized controlled trials
This meta-analysis suggests that chitosan may have a small but statistically significant effect on body weight.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.