Cat's Claw
An Amazonian vine with potent anti-inflammatory and immune-modulating properties.
Also known as: Uncaria tomentosa • Uña de Gato
Overview
Cat's claw (Uncaria tomentosa) is a large, woody vine that grows in the Amazon rainforest and other tropical areas of Central and South America. It gets its name from the sharp, curved thorns that grow along the vine, resembling the claws of a cat. The inner bark and root of the plant have been used for centuries in traditional medicine to treat a wide variety of ailments, particularly inflammatory conditions and immune system disorders. Cat's claw contains a complex array of active compounds, including pentacyclic oxindole alkaloids (POAs), quinovic acid glycosides, and polyphenols. These compounds are believed to be responsible for its therapeutic effects. Research suggests that cat's claw has significant anti-inflammatory properties, which may help to relieve symptoms of osteoarthritis and rheumatoid arthritis. It is also known as an immune modulator, meaning it can help to balance and support the immune system. Some studies indicate it can enhance the activity of white blood cells, which are crucial for fighting off infections. Additionally, cat's claw possesses antioxidant properties, helping to protect cells from damage by free radicals. It is most commonly available in capsule, tablet, or liquid extract form.
Key Benefits
Reduces Arthritis Pain and Inflammation
Studies have shown that cat's claw can effectively reduce pain and swelling in individuals with osteoarthritis and rheumatoid arthritis.
Modulates the Immune System
It can help to balance the immune system, potentially boosting a weak immune system or calming an overactive one, which is beneficial for autoimmune conditions.
Provides Antioxidant Support
The herb contains powerful antioxidants that help protect cells from oxidative stress and damage.
Dosage & How to Take
Dosage depends on the form and the condition being treated. It is important to use products standardized for their alkaloid content.
| Purpose | Dose | Notes |
|---|---|---|
| Osteoarthritis | 100 mg of a specific extract daily | Studies have used specific proprietary extracts. |
| Rheumatoid Arthritis | 60 mg of a specific extract daily | Taken in three divided doses. |
| General Immune Support | 250-500 mg of extract | Taken once or twice daily. |
Best Time to Take
Can be taken with meals to reduce potential stomach upset.
With or Without Food
Recommended to take with food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules/Tablets | Medium | Convenient and standardized dosing. | Look for extracts standardized to contain a certain percentage of oxindole alkaloids. |
| Liquid Extract/Tincture | Medium | Flexible dosing. | May have a bitter taste. |
Side Effects & Safety
Common
- Dizziness
- Headache
- Nausea
Rare
- Lowered blood pressure
- Increased risk of bleeding
- Kidney problems (in one reported case)
Contraindications
- Autoimmune diseases (e.g., lupus, MS) without medical supervision
- Pregnancy and breastfeeding
- Upcoming surgery
- Leukemia
- Low blood pressure
Interactions
May counteract the effects of drugs that suppress the immune system.
May increase the effect of these drugs, leading to hypotension.
May increase the risk of bleeding.
Scientific Research
Efficacy and safety of cat's claw (Uncaria tomentosa) in an adult population with acute pharyngitis
Cat's claw was shown to be effective in reducing symptoms of acute pharyngitis (sore throat).
Cat's claw: a promising herbal medicine for the treatment of neurodegenerative diseases
The anti-inflammatory and antioxidant properties of cat's claw show potential for treating diseases like Alzheimer's and Parkinson's.
Food Sources
Products With Cat's Claw
4 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.