Bromelain

A protein-digesting enzyme from pineapple that helps reduce mucus and inflammation.

Also known as: Pineapple Extract • Bromelain for Lungs

other Names
Ananas comosus extract
primary Benefits
Thins mucus, reduces sinus inflammation, aids digestion.
common Dose
500-1000 mg (providing 2400 GDU) per day
best Form
Enteric-coated tablets
timing
Between meals for anti-inflammatory effects, with meals for digestion.
safety Rating
Generally safe, but can cause allergic reactions in some.

Overview

Bromelain is a complex of enzymes extracted from the stem and fruit of the pineapple plant. It is a proteolytic enzyme, meaning it helps digest protein. In the context of respiratory health, bromelain is valued for its mucolytic and anti-inflammatory properties, helping to thin respiratory mucus and reduce swelling in the nose and sinuses.

Key Benefits

Mucolytic Properties

Helps to break down and thin mucus, making it easier to clear from the respiratory tract.

Anti-inflammatory Action

Reduces inflammation and swelling in the sinuses and airways, relieving congestion.

Enhances Quercetin Absorption

Often paired with quercetin to improve its absorption and provide synergistic anti-inflammatory benefits.

Dosage & How to Take

For respiratory benefits, take 500 mg between meals, two to three times daily.

PurposeDoseNotes
Sinusitis/Respiratory Congestion500-1000 mg/dayTaken in divided doses between meals.
Digestive Aid500 mgTaken with meals.

Best Time to Take

Take between meals for systemic anti-inflammatory and mucolytic effects. Take with meals to aid protein digestion.

With or Without Food

Avoid taking with food for respiratory benefits.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Tablets/CapsulesGoodGeneral use.Look for GDU (Gelatin Digesting Units) on the label to ensure potency.
Enteric-Coated TabletsEnhancedProtecting the enzyme from stomach acid.Ideal for systemic effects.

Side Effects & Safety

Common

  • Stomach upset
  • Diarrhea

Rare

  • Allergic reactions (especially in those allergic to pineapple)
  • Increased heart rate

Contraindications

  • Avoid if allergic to pineapple, latex, or certain pollens.
  • Use with caution if you have a bleeding disorder or are taking blood thinners.

Interactions

Blood Thinners (e.g., Warfarin, Aspirin)High

Increases the risk of bleeding.

Antibiotics (e.g., Amoxicillin, Tetracycline)Moderate

May increase the absorption and effects of these antibiotics.

SedativesModerate

May increase the sedative effect.

Scientific Research

2012Biotechnology Research International

The role of bromelain in clinical and therapeutic applications

A review highlighted bromelain's efficacy in treating sinusitis and reducing inflammation and mucus production.

Food Sources

Pineapple (especially the core/stem)

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.