Ashwagandha (Thyroid Support)
An adaptogenic herb clinically shown to normalize thyroid hormone levels in subclinical hypothyroidism.
Also known as: Withania somnifera • Indian Ginseng • Winter Cherry
Overview
Ashwagandha (Withania somnifera) is an Ayurvedic adaptogen with emerging evidence for thyroid support. A landmark RCT showed that ashwagandha root extract significantly increased serum T3 and T4 levels while normalizing TSH in patients with subclinical hypothyroidism. The mechanism likely involves HPA axis modulation and direct stimulation of thyroid activity.
Key Benefits
Thyroid Hormone Normalization
RCT showed significant increases in T3 and T4 with TSH normalization in subclinical hypothyroidism.
Cortisol Reduction
Reduces cortisol levels, which can suppress thyroid function when chronically elevated.
HPA Axis Support
Modulates the hypothalamic-pituitary-adrenal axis, which interacts with thyroid regulation.
Stress Resilience
Reduces perceived stress and anxiety, which can impair thyroid function.
Dosage & How to Take
300-600 mg daily of root extract.
| Purpose | Dose | Notes |
|---|---|---|
| Thyroid support | 600 mg/day | As studied in the thyroid RCT |
| General adaptogenic | 300-600 mg/day | KSM-66 or Sensoril |
Best Time to Take
Morning or evening.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| KSM-66 Root Extract | Good | Most researched form | Full-spectrum root extract. |
| Sensoril Root + Leaf Extract | Good | Higher withanolide content | More calming effect. |
Side Effects & Safety
Common
- Mild drowsiness
- GI discomfort
Rare
- Thyroid overstimulation
- Liver enzyme elevation (rare)
Contraindications
- Hyperthyroidism
- Graves' disease
- Pregnancy
- Autoimmune conditions (consult doctor)
Interactions
May enhance thyroid hormone levels; requires monitoring.
May enhance sedative effects.
Scientific Research
Ashwagandha and subclinical hypothyroidism
RCT showed 600 mg/day ashwagandha root extract significantly improved serum T3, T4, and TSH levels vs placebo over 8 weeks.
Food Sources
Products With Ashwagandha (Thyroid Support)
11 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.