Andrographis Extract
The 'King of Bitters' used in Ayurveda and TCM for upper respiratory infections and immune defense.
Also known as: King of Bitters • Kalmegh • Green Chiretta
Overview
Andrographis paniculata is a bitter herb used extensively in Ayurvedic and traditional Chinese medicine. Its primary active compound, andrographolide, has potent anti-inflammatory, antiviral, and immune-stimulating properties. It is one of the most well-studied herbs for upper respiratory tract infections.
Key Benefits
Upper Respiratory Support
Multiple clinical trials show reduced severity and duration of colds and flu.
Immune Stimulation
Andrographolide enhances immune cell activity and antibody production.
Anti-Inflammatory
Inhibits NF-kB and COX-2 inflammatory pathways.
Liver Protection
Hepatoprotective effects demonstrated in multiple studies.
Dosage & How to Take
200-400 mg standardized extract daily.
| Purpose | Dose | Notes |
|---|---|---|
| Prevention | 200 mg/day | During cold/flu season |
| Acute illness | 400 mg/day | At first sign of symptoms, for 5-7 days |
Best Time to Take
At first sign of illness for acute use.
With or Without Food
With food to reduce bitterness.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Standardized Extract Capsules | Good | Precise andrographolide dosing | Standardized to 10-30% andrographolides. |
| Tincture | Good | Quick absorption | Extremely bitter taste. |
| Combination Formulas | Good | Synergistic effects | Often combined with Siberian ginseng. |
Side Effects & Safety
Common
- Bitter taste
- Mild GI discomfort
- Headache
Rare
- Allergic reactions
- Anaphylaxis (very rare)
Contraindications
- Pregnancy (may be abortifacient)
- Autoimmune conditions
- Gallbladder disease
Interactions
May enhance anticoagulant effects.
May lower blood pressure.
May counteract immunosuppressive effects.
Scientific Research
Andrographis for upper respiratory infections
Cochrane review found andrographis significantly reduced symptoms of acute upper respiratory tract infections.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.